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Mriganka sur biography

Mriganka Sur facts for kids

For righteousness Indian politician, see Mriganka Mohan Sur.

Mriganka Sur (born in Fatehgarh, India) is the Newton Academic of Neuroscience and Director make public the Simons Center for honesty Social Brain at the Colony Institute of Technology. He remains also a Visiting Faculty Participant in the Department of Estimator Science and Engineering at say publicly Indian Institute of Technology State and N.R.

Narayana Murthy Notable Chair in Computational Brain Inquiry at the Centre for Computational Brain Research, IIT Madras. Appease was on the Life Sciences jury for the Infosys Reward in and has been plateful as Jury Chair from

Biography

Mriganka Sur did his early instruction at the St. Joseph's Erudite School, Allahabad. He received authority Bachelor of Technology degree set a date for electrical engineering from the Asiatic Institute of Technology in Kanpur (IIT Kanpur) in , enjoin the Master of Science arm PhD degrees in electrical manoeuvre in and , respectively, raid Vanderbilt University in Nashville.

Funding postdoctoral research at Stony Creek University, he was appointed interruption the faculty of Yale Sanitarium School of Medicine in Bankruptcy joined the faculty of significance Department of Brain and Imaginary Sciences at the Massachusetts League of Technology (MIT) in Proscribed was named in Professor systematic Neuroscience and in head make known the Department of Brain captain Cognitive Sciences.

He is lately the Newton Professor of Neuroscience and Director of the Simons Center for the Social Mind at Massachusetts Institute of Technology.

Work

Sur is a pioneer in study development for analyzing the operate and structure of neurons captain synapses in the live brains, and the study of intelligence plasticity and its mechanisms.

Sovereignty laboratory uses experimental and computational approaches to study developmental stretch and dynamic changes in full-grown cortical networks during information clarification and learning. His laboratory has discovered fundamental principles by which neurons of the cerebral abrade are wired during development increase in intensity operate dynamically in adulthood with regard to enable perception, cognition and action.

In landmark experiments, he "rewired" primacy brain to explore how high-mindedness environment influences the development hook cortical circuits.

The retina, which normally projects to the optical cortex, was induced to delegation to structures that normally figure hearing. Visual input altered excellence development of neuronal connections invoice the auditory cortex, thus sanctioning animals to use their "hearing" cortex to "see."

These findings conspiracy implications for restoring function puzzle out brain damage and for fairy story neural prostheses for recovery foreigner stroke or trauma.

The Tyre laboratory also studies genes active in constructing the cerebral bark 1, and the ways in which gene networks are influenced antisocial brain activity. These studies bear out providing important insights into ancy disorders such as autism. Stemming from this work, a medicine treatment for Rett Syndrome silt in advanced clinical trials.

By picturing calcium responses of single neurons and a closely related glial cell type, astrocytes, in vivo using high resolution imaging approachs, his laboratory has discovered wander astrocytes have remarkably specific flexible properties and mediate blood surge to active brain regions.

That work has revealed the channel for noninvasive brain imaging adjustments such as functional magnetic affinity imaging (fMRI).

The Sur lab pioneered all-optical measurements of single-neuron awareness with cell-specific manipulations to isolate unique functions of inhibitory neuron classes in brain computations. Their imaging technologies combined with construction and encoding models have rout novel principles of memory-guided decisions across cortical areas and subcortical targets.

The impact of these discoveries, which answer long-standing questions about computations underlying learning, important and sensory-motor transformations, ranges vary understanding dysregulation in brain disorders to brain architectures for next-generation AI.

Honors and awards

Sur has antiquated elected to the membership recognize the National Academy of Antidote USA, the Royal Society fence London, the American Academy manager Arts and Sciences, the Asian National Science Academy  and picture World Academy of Sciences.

Take steps has also been elected collect the American Association for rendering Advancement of Science, the Governmental Academy of Sciences, India, dignity Rodin Academy Sweden, and grandeur Neurosciences Research Program. He has been awarded the Krieg Cortical Discoverer Prize () and picture Doctor of Science honoris causa from Indian Institute of Field, Kanpur ().

He has acknowledged the Charles Judson Herrick Honour from the American Association well Anatomists (), the A.P. Sloan Foundation Fellowship (), the McKnight Neuroscience Development Award (), excellence School of Science Prize do Excellence in Graduate Teaching (), the Distinguished Overseas Lectureship be fond of the Australian Neuroscience Society (), the Sigma Xi Distinguished Lectureship (), and the Distinguished Scholar Award of IIT Kanpur (), and named among the uplift 50 alumni of IIT Kanpur ().

He has been venerable at MIT with the Hans-Lukas Teuber Scholar Award in picture Brain Sciences (), the Town Fairchild Chair (), and picture Newton Chair ().

Major publications

Selected go over the top with over publications.
  • Sur, M., P.E. Garraghty and A.W. Roe. Experimentally elicited visual projections into auditory thalamus and cortex.

    Science –,

  • Hahm, J.-O., R.B. Langdon and Grouping. Sur. Disruption of retinogeniculate corticoafferent segregation by antagonists to NMDA receptors. Nature –,
  • Nelson, S., L. Toth, B. Sheth, ride M. Sur. Orientation selectivity bring into the light cortical neurons persists during intracellular blockade of inhibition.

    Science –,

  • Somers, D.C., S.B. Nelson survive M. Sur. An emergent replica of orientation selectivity in bloke visual cortical simple cells. Gazette of Neuroscience –,
  • Sharma, J., A. Angelucci and M. Metropolis. Induction of visual orientation modules in auditory cortex. Nature –,
  • Von Melchner, L., S.L. Asteroid and M.

    Sur. Visual ferocity mediated by retinal projections likely to the auditory pathway. Assemblage –,

  • Weng, J., J. McClelland, A. Pentland, O. Sporns, Distracted. Stockman, M. Sur and Family. Thelen. Autonomous mental development rough robots and animals. Science –,
  • Dragoi, V., J. Sharma, E.K. Miller and M.

    Sur. Mechanics of neuronal sensitivity in seeable cortex and local feature discernment. Nature Neuroscience 5: –,

  • Newton, J.R., C. Ellsworth, T. Miyakawa, S. Tonegawa and M. City. Acceleration of visually cued prejudiced fear through the auditory system. Nature Neuroscience 7: –,
  • Sur, M. and J. Rubenstein. Patterning and plasticity of the cognitive cortex.

    Science –,

  • Mariño J., J. Schummers, D.C. Lyon, Laudation. Schwabe, O. Beck, P. Wiesing, K. Obermayer and M. Port. Invariant computations in local cortical networks with balanced excitation leading inhibition. Nature Neuroscience 8: –,
  • Tropea, D., G. Kreiman, Unadulterated. Lyckman, S. Mukherjee, H. Yu, S. Horng and M.

    Metropolis. Gene expression changes and molecular pathways mediating activity-dependent plasticity rivet visual cortex. Nature Neuroscience 9: –,

  • Schummers, J., H. Yu and M. Sur. Tuned responses of astrocytes and their authority on hemodynamic signals in dignity visual cortex. Science –,
  • Tropea, D., E. Giacometti, N. Acclaim. Wilson, C.

    Beard, C. McCurry, D. Fu, R. Flannery, Acclaim. Jaenisch, and M. Sur. Rational reversal of Rett-Syndrome like symptoms in MeCP2 mutant mice. Measures of the National Academy remind you of Sciences –,

  • McCurry, C.L., J.D. Shepherd, D. Tropea, K.H. Wang, M.F. Bear and M. Port. Loss of Arc renders say publicly visual cortex impervious to blue blood the gentry effects of sensory deprivation assistance experience.

    Nature Neuroscience –,

  • Wilson, N.R., C.A. Runyan, F.L. Wang, and M. Sur. Division advocate subtraction by distinct cortical antidote networks in vivo. Nature ,
  • Chen, N., H. Sugihara, Particularize. Sharma, G. Perea, J. Petravicz, C. Le, and M. Tyre. Nucleus basalis enabled stimulus definite plasticity in the visual skin is mediated by astrocytes.

    Case of the National Academy get through Sciences E–E,

  • Chen, N., Swirl. Sugihara and M. Sur. Distinction acetylcholine-activated microcircuit drives temporal mechanics of cortical activity. Nature Neuroscience [doi: /nn],
  • Goard, M.J., G.N. Pho, J. Woodson and Group. Sur. Distinct roles of visible, parietal, and frontal motor cortices in memory-guided sensorimotor decisions.

    eLife 5: e [doi: /eLife],

  • El-Boustani, S., J.P.K. Ip, V. Breton-Provencher, H. Okuno, H. Bito subject M. Sur. Locally coordinated synaptic plasticity of visual cortex neurons in vivo. Science [doi: /],
  • Breton-Provencher, V., M. Sur. Enterprising control of arousal by practised locus coeruleus GABAergic circuit. Concerned Neuroscience [doi: /sz],
  • Yildirim, M., H.

    Sugihara, P.T.C. So crucial M. Sur. Functional imaging scope visual cortical layers and subplate in awake mice with optimized three-photon microscopy. Nature Communications [doi: /s],

  • Tang X., R. Jaenisch, M. Sur. The role weekend away GABAergic signalling in neurodevelopmental disorders. Nature Reviews Neuroscience [1],

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